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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTPS All Species: 53.64
Human Site: T110 Identified Species: 90.77
UniProt: P17812 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17812 NP_001896.2 591 66690 T110 K G D Y L G K T V Q V V P H I
Chimpanzee Pan troglodytes XP_524681 591 66712 T110 K G D Y L G K T V Q V V P H I
Rhesus Macaque Macaca mulatta XP_001084608 591 66746 T110 K G D Y L G K T V Q V V P H I
Dog Lupus familis XP_537968 586 65447 T110 R G D Y L G K T V Q V V P H I
Cat Felis silvestris
Mouse Mus musculus P70698 591 66664 T110 K G D Y L G K T V Q V V P H I
Rat Rattus norvegicus Q5U2N0 586 65655 T110 R G D Y L G K T V Q V V P H I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506472 591 66548 T110 K G D Y L G K T V Q V V P H I
Chicken Gallus gallus Q5F3Z1 586 66050 T110 H G D Y L G K T V Q V V P H I
Frog Xenopus laevis Q5XHA8 591 66854 T110 K G D Y L G K T V Q V V P H I
Zebra Danio Brachydanio rerio Q6PEI7 591 66577 T110 R G D Y L G K T V Q V V P H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUL1 627 69429 T110 T G E Y L G K T V Q V V P H I
Honey Bee Apis mellifera XP_624223 604 67926 T110 H G D Y L G K T V Q V I P H I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P28274 579 64692 T110 K G D Y L G K T V Q I V P H L
Red Bread Mold Neurospora crassa Q7RZV2 568 63157 R116 A I I D T I N R V S R V P V D
Conservation
Percent
Protein Identity: 100 99.6 99.4 75.3 N.A. 97.8 74.1 N.A. 94.7 76.9 89.1 86.6 N.A. 63.3 65.5 N.A. N.A.
Protein Similarity: 100 99.8 99.8 85.2 N.A. 98.3 85.1 N.A. 97.1 87.6 95.5 92.8 N.A. 77 79.1 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 100 93.3 100 93.3 N.A. 86.6 86.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 100 100 N.A. 93.3 93.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 57.1 51.7
Protein Similarity: N.A. N.A. N.A. N.A. 72.5 68.1
P-Site Identity: N.A. N.A. N.A. N.A. 86.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 100 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 86 8 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 93 0 0 0 93 0 0 0 0 0 0 0 0 0 % G
% His: 15 0 0 0 0 0 0 0 0 0 0 0 0 93 0 % H
% Ile: 0 8 8 0 0 8 0 0 0 0 8 8 0 0 86 % I
% Lys: 50 0 0 0 0 0 93 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 93 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 93 0 0 0 0 0 % Q
% Arg: 22 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % S
% Thr: 8 0 0 0 8 0 0 93 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 100 0 86 93 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _